ALEX SCHIFFER

Biotech Researcher

Research biologist with broad experience designing, executing, and analyzing pre-clinical experiments. Comfortable performing and evaluating both in vitro and in vivo studies across multiple therapeutic modalities (ASOs, SM, GTx).

Established record of successfully developing and validating assays, including ELISA, MSD, HTRF, RT-qPCR, and many others. Assay development work includes optimization and miniaturization of biochemical and molecular biology assays into 96-well and 384-well formats, as well as conversion of manual protocols to automation compatible formats. Significant experience with established cell lines, stem cells, primary neuromuscular patient cultures, oncology lines, and iPSC-derived motor neurons.

Work Experience

Atlas Venture, New Company

Senior Research Associate
01/2020 - Present

Responsible for assay development and validation.

Biogen

Associate Scientist II
DEC 2018 - JAN 2020

Investigated multiple therapeutic modalities for treatment of Spinal Muscular Atrophy (SMA). Worked on in-vitro and in-vivo efficacy studies for IND filing.

Boston Children's Hospital

Research Assistant III
OCT 2016 - DEC 2018

Investigated genetic mechanisms of blood vessel development using knock-down and knock-out techniques in Danio rerio (zebrafish) and Mus musculus (mice).

Northeastern University

Molecular Research Intern
AUG 2016 - OCT 2016

Investigated oxidative stress response and their effect on aging in C. elegans (nematodes) using CRISPR/Cas9 to introduce specific mutations into candidate genes.

University of Central Florida

Undergraduate Research Assistant
JAN 2013 - MAY 2015

Investigated distribution and diversity of zooplankton across the United States using custom R scripts and large EPA data sets.

Education

Boston University

M.Eng. Biomedical Engineering
May 2016

University of Central Florida

B.S. Biology
May 2015

Skills